Elevated serum uric acid is associated with the risk of advanced staging and vascular involvement in patients with hepatoblastoma: a 14-year retrospective study

BackgroundUric acid is the end product of the purine metabolism abc material pathway, and has been linked to cancer risks and prognosis, but its relationship with hepatoblastoma (HB) remains unclear.This study aims to investigate the association between serum uric acid (SUA) and the advanced tumor staging and unfavorable extra-parenchymal tumor cha

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Characterization, Recombinant Production and Structure-Function Analysis of NvCI, A Picomolar Metallocarboxypeptidase Inhibitor from the Marine Snail Nerita versicolor

A very powerful proteinaceous inhibitor of metallocarboxypeptidases has been isolated from the marine snail Nerita versicolor and characterized in depth.The most abundant of four, very similar isoforms, NvCla, was taken as reference and N-terminally sequenced to obtain a 372-nucleotide band coding for the protein cDNA.The mature protein contains 53

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Edge of Chaos in Memristor Cellular Nonlinear Networks

Information processing in the guerlain ideal cologne brain takes place in a dense network of neurons connected through synapses.The collaborative work between these two components (Synapses and Neurons) allows for basic brain functions such as learning and memorization.The so-called von Neumann bottleneck, which limits the information processing ca

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